Gadolinium Imaging Contrast Agents
On May 23, 2007 the Food and Drug Administration (FDA) issued a public health advisory warning the public regarding recent findings that gadolinium-based MRI contrasting agents significantly increased the risk of Nephrogenic Systemic Fibrosis (NSF). Currently there are 5 MRI contrasting agents that use gadolinium:
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OmniScan - Gadadiamide
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OptiMARK - Gadoversetamide
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Prohance - Gadoteridol
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Magnavist - Gadopentetate Dimeglumine
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Multihance - Gadobenate Dimeglumine
Gadolinium-based injections are used as an MRI contrast agent so doctors can better distinguish blood vessels from nearby tissue. For those with impaired kidney function, gadolinium-based MRI contrast agents could lead to a serious and potentially fatal disorder called Nephrogenic Systemic Fibrosis.
What is Nephrogenic Systemic Fibrosis?
NSF is a progressive disorder which is associated with the development of excessive scar tissue and thick, hardened and tight areas of skin which often cover the joints, resulting in severe limitations on movement. In many cases it renders the victim unable to walk or fully move the joints of their arms, hands, legs and/or feet, and they become dependent on a wheelchair within weeks of the onset. There is no known cure or effective treatment for Nephrogenic Systemic Fibrosis, and in some cases it can lead to death.
Gadolinium Side Effects
Less severe gadolinium side effects after receiving the contrast injection could include allergic reactions which can lead to skin conditions, such as rashes, sweating, itching, hives and swelling of the face. It can also cause irritation to the veins where it is injected, causing skin problems and possible formation of blood clots. Signs of more severe side effects may include:
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- Burning, itching, swelling, hardening and tightening of the skin
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- Red or dark patches on the skin
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- Yellow spots on the whites of the eyes
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- Stiff joints with trouble straightening or moving the limbs
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- Pain in the hip bones or ribs
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- Generalized muscle weakness
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If you or a loved one have experienced gadolinium side effects you may be entitled to compensation. Contact the gadolinium attorneys of Ennis & Ennis today for a free confidential case evaluation. Our on-staff nurse and lawyers are standing by to answer any questions you may have regarding gadolinium side effects or any type of gadolinium litigation.
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