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Astrazeneca gets mixed response to Seroquel

-FinancialTimes

04/10/2009 - AstraZeneca’s hopes of extending the uses of its blockbuster drug Seroquel in the US have met with a mixed response from a key panel of medical experts.

The extended release form of Seroquel is currently approved in the US for the treatment of schizophrenia and bipolar disorder. Global sales of Seroquel were $4.5bn last year, making it AstraZeneca’s second biggest selling drug.

The US Food and Drug Administration psychopharmacologic drugs advisory committee said on Wednesday that the extended release form of Seroquel could also be used alongside other drug treatments for major depression.

However, it said it was not safe enough for its stand-alone use against major depression to be justified, nor as a treatment for generalised anxiety disorder, even though it was effective in both instances.

The FDA, which regulates new drugs, normally follows the advice of its medical committees. AstraZeneca said it was pleased with the approval and would have further discussions with the FDA.

The health concerns cited by the advisory committee were linked to possible heart failure, involuntary movements and metabolic issues such as weight gain. Seroquel is the subject of litigation in the US brought by patients who claim it caused diabetes.

If you or a loved one have experienced any of the serious Seroquel side effects such as hyperglycemia or diabetes during or after Seroquel treatment, you may be entitled to compensation. Contact the Seroquel attorneys of Ennis & Ennis today for a free confidential case evaluation. Our on staff nurse and lawyers are standing by to answer any questions you may have regarding Seroquel side effects, a possible Seroquel class action lawsuit, or any other type of Seroquel litigation.